Governo Italiano
Produzione Scientifica
Questa sezione raccoglie l'elenco delle pubblicazioni scientifiche realizzate dall'Istituto di Scienze Biomediche della Difesa nei settori altamente specializzati in cui esercita il suo ruolo di ricerca e sviluppo.
La produzione scientifica è il frutto di collaborazioni interdisciplinari e rappresenta il contributo dell'ISBD alla comunità scientifica nazionale e internazionale per l'accrescimento e il costante aggiornamento delle conoscenze avanzate, applicate alle aree di interesse della sicurezza sanitaria e della difesa:
2025
- Chimienti S, Di Spirito M, Molinari F, Rozov O, Lista F, D'Amelio R, Salemi S, Fillo S. Botulinum Neurotoxins as Two-Faced Janus Proteins. Biomedicines. 2025 Feb 8;13(2):411. doi: 10.3390/biomedicines13020411. PMID: 40002825; PMCID: PMC11853235.
- Rossi A, Bassi G, Cunha C, Baldisserri C, Ravaglia N, Gardini D, Molinari F, Lista F, Teran FJ, Piperno A, Montesi M, Panseri S. Magnetically induced anisotropic structure in an injectable hydrogel for skeletal muscle regeneration. J Colloid Interface Sci. 2025 Jan 15;678(Pt C):334-345. doi: 10.1016/j.jcis.2024.09.121. Epub 2024 Sep 16. PMID: 39298986.
- Spagnolo F, Lista F, Curcio C. Dataset of SARS-CoV-2 spike protein receptor binding domain variants in complex with antigen-binding fragments targeting COVID-19 vaccine-referenced variants. Data Brief. 2025 Jan 11;58:111291. doi: 10.1016/j.dib.2025.111291. PMID: 39906132; PMCID: PMC11791151.
- Cavalli M, Campoli G, Anselmo A, Brandi R, Fortunato A, Di Spirito M, Monte A, Lipari M, Bortone M, Fain VV, D'Amelio R, Lista F, Fillo S. Next generation sequencing of multiple SARS-CoV-2 infections in the Omicron Era. Sci Rep. 2025 Jan 27;15(1):3372. doi: 10.1038/s41598-024-84952-6. PMID: 39870695; PMCID: PMC11772649.
- Scaturro M, Lanni A, Mancini F, Girolamo A, Fillo S, Ciammaruconi A, Lista F, Cocuzza CE, Musumeci R, Ginevra C, Descours G, Jarraud S, Iera J, Visca P, Ricci ML. Antimicrobial susceptibility and epidemiological types of Legionella pneumophila human isolates from Italy (1987-2020). J Glob Antimicrob Resist. 2025 Mar;41:181-188. doi: 10.1016/j.jgar.2024.12.030. Epub 2025 Jan 15. PMID: 39824283.
- Tidu L, Ciccarelli S, De Sanctis S, Lista F, Ferreri R, Regalbuto E, Grizzi F, Taverna G, Poli A, Bruzzone M, Ceppi M, Roggieri P, Bolognesi C. Sentinel role of military dogs in detecting genotoxic agents in the environment during military operations: a pilot study. Toxicol Mech Methods. 2025 Jan 26:1-9. doi: 10.1080/15376516.2025.2453731. Epub ahead of print. PMID: 39819395.
2024
- Brandi R, Paganelli A, D'Amelio R, Giuliani P, Lista F, Salemi S, Paganelli R. mRNA Vaccines Against COVID-19 as Trailblazers for Other Human Infectious Diseases. Vaccines (Basel). 2024 Dec 16;12(12):1418. doi: 10.3390/vaccines12121418. PMID: 39772079; PMCID: PMC11680146.
- Faggioni G, Moramarco F, Luciano E, De Santis R, Amoroso A, Petralito G, Molinari F, Grosso P, Rozov O, Morelli D, Carbone D, Lista F. Quantitative IgG response to SARS-CoV-2 membrane protein in infected individuals strongly correlates with lung injury. Sci Rep. 2024 Dec 28;14(1):30665. doi: 10.1038/s41598-024-78381-8. PMID: 39730423; PMCID: PMC11681004.
- La Sorda M, Palucci I, Natalini D, Fillo S, Giordani F, Paglione F, Monte A, Lista F, Mancini F, Girolamo A, Rota MC, Caporali MG, Ricci R, Ginevra C, Jarraud S, Sanguinetti M, Scaturro M, Ricci ML. Case report: First report of Legionella pneumophila and Bordetella bronchiseptica coinfection in an immunocompromised patient. Front Med (Lausanne). 2024 Oct 22;11:1470567. doi: 10.3389/fmed.2024.1470567. PMID: 39502646; PMCID: PMC11534721.
- Murdocca M, Andrade Santos-Filho O, De Masi C, Dos Santos Rodrigues E, Campos de Souza CV, De Santis R, Amatore D, Latini A, Schipani R, di Rienzo Businco L, Brandimarte B, Grilli G, Huang TL, Mayence AS, Lista F, Duranti A, Sangiuolo F, Vanden Eynde JJ, Novelli G. Characterization of the symmetrical benzimidazole twin drug TL1228: the role as viral entry inhibitor for fighting COVID-19. Biol Direct. 2024 Oct 16;19(1):93. doi: 10.1186/s13062-024-00523-9. PMID: 39415197; PMCID: PMC11481581.
- Fiore L, Mazzaracchio V, Antinucci A, Ferrara R, Sciarra T, Lista F, Shen AQ, Arduini F. Wearable electrochemical device based on butterfly-like paper-based microfluidics for pH and Na+ monitoring in sweat. Mikrochim Acta. 2024 Sep 7;191(10):580. doi: 10.1007/s00604-024-06564-1. PMID: 39243287; PMCID: PMC11380643.
- Rossi A, Furlani F, Bassi G, Cunha C, Lunghi A, Molinari F, Teran FJ, Lista F, Bianchi M, Piperno A, Montesi M, Panseri S. Contactless magnetically responsive injectable hydrogel for aligned tissue regeneration. Mater Today Bio. 2024 Jun 3;27:101110. doi: 10.1016/j.mtbio.2024.101110. PMID: 39211510; PMCID: PMC11360152.
- Massaro L, De Sanctis S, Franchini V, Regalbuto E, Alfano G, Focaccetti C, Benvenuto M, Cifaldi L, Sgura A, Berardinelli F, Marinaccio J, Barbato F, Rossi E, Nardozi D, Masuelli L, Bei R, Lista F. Study of genotoxic and cytotoxic effects induced in human fibroblasts by exposure to pulsed and continuous 1.6 GHz radiofrequency. Front Public Health. 2024 Jul 31;12:1419525. doi: 10.3389/fpubh.2024.1419525. PMID: 39145180; PMCID: PMC11323689.
- Mariotti S, Venturi G, Chiantore MV, Teloni R, De Santis R, Amendola A, Fortuna C, Marsili G, Grilli G, Lia MS, Kiros ST, Lagi F, Bartoloni A, Iacobino A, Cresta R, Lastilla M, Biselli R, Di Bonito P, Lista F, Nisini R. Antibodies Induced by Smallpox Vaccination after at Least 45 Years Cross-React with and In Vitro Neutralize Mpox Virus: A Role for Polyclonal B Cell Activation? Viruses. 2024 Apr 17;16(4):620. doi: 10.3390/v16040620. PMID: 38675961; PMCID: PMC11054675.
- Campagna R, Dominelli F, Zingaropoli MA, Ciurluini F, Grilli G, Amoroso A, De Domenico A, Amatore D, Lia MS, Cortesi E, Picone V, Mastroianni CM, Ciardi MR, De Santis R, Lista F, Antonelli G, Turriziani O. COVID-19 vaccination in cancer patients: Immune responses one year after the third dose. Vaccine. 2024 Apr 11;42(10):2687-2694. doi: 10.1016/j.vaccine.2024.03.017. Epub 2024 Mar 17. PMID: 38499458.
- Vacca P, Fazio C, Neri A, Ambrosio L, Carannante A, Lista F, Fillo S, Ciammaruconi A, Fortunato A, Stefanelli P. Antimicrobial susceptibility profiles and genotyping of Neisseria meningitidis of serogroup C, Italy, 2000-2020. Front Microbiol. 2024 Jan 3;14:1272123. doi: 10.3389/fmicb.2023.1272123. PMID: 38235426; PMCID: PMC10791874.
- Fabiani L, Fiore L, Fillo S, D'Amore N, De Santis R, Lista F, Arduini F. Smartphone-assisted paper-based electrochemical immunosensor for SARS-CoV-2 detection in saliva. Bioelectrochemistry. 2024 Apr;156:108619. doi: 10.1016/j.bioelechem.2023.108619. Epub 2023 Nov 29. PMID: 38128441.
- Antonelli G, Focosi D, Turriziani O, Tuccori M, Brandi R, Fillo S, Ajassa C, Lista F, Mastroianni CM. Corrigendum to "Virological and clinical rebounds of COVID-19 soon after nirmatrelvir/ritonavir discontinuation" [Clin Microbiol Infect 28 (12) (2022 Dec) 1657-1658]. Clin Microbiol Infect. 2024 Mar;30(3):408. doi: 10.1016/j.cmi.2023.12.014. Epub 2023 Dec 14. Erratum for: Clin Microbiol Infect. 2022 Dec;28(12):1657-1658. doi: 10.1016/j.cmi.2022.06.029. PMID: 38103639; PMCID: PMC11021203.
2023
- Vacca P, Fazio C, Neri A, Ambrosio L, Carannante A, Lista F, Fillo S, Ciammaruconi A, Fortunato A, Stefanelli P. Antimicrobial susceptibility profiles and genotyping of Neisseria meningitidis of serogroup C, Italy, 2000-2020. Front Microbiol. 2024 Jan 3;14:1272123. doi: 10.3389/fmicb.2023.1272123. PMID: 38235426; PMCID: PMC10791874.
- Fabiani L, Fiore L, Fillo S, D'Amore N, De Santis R, Lista F, Arduini F. Smartphone-assisted paper-based electrochemical immunosensor for SARS-CoV-2 detection in saliva. Bioelectrochemistry. 2024 Apr;156:108619. doi: 10.1016/j.bioelechem.2023.108619. Epub 2023 Nov 29. PMID: 38128441.
- Antonelli G, Focosi D, Turriziani O, Tuccori M, Brandi R, Fillo S, Ajassa C, Lista F, Mastroianni CM. Corrigendum to "Virological and clinical rebounds of COVID-19 soon after nirmatrelvir/ritonavir discontinuation" [Clin Microbiol Infect 28 (12) (2022 Dec) 1657-1658]. Clin Microbiol Infect. 2024 Mar;30(3):408. doi: 10.1016/j.cmi.2023.12.014. Epub 2023 Dec 14. Erratum for: Clin Microbiol Infect. 2022 Dec;28(12):1657-1658. doi: 10.1016/j.cmi.2022.06.029. PMID: 38103639; PMCID: PMC11021203.
- Manna A, De Forni D, Bartocci M, Pasculli N, Poddesu B, Lista F, De Santis R, Amatore D, Grilli G, Molinari F, Sangiovanni Vincentelli A, Lori F. Reply to Taylor et al. Comment on "Manna et al. SARS-CoV-2 Inactivation in Aerosol by Means of Radiated Microwaves. Viruses 2023, 15, 1443". Viruses. 2023 Oct 18;15(10):2111. doi: 10.3390/v15102111. PMID: 37896888; PMCID: PMC10612018.
- Mögling R, Reimerink J, Stanoeva KR, Keramarou M, Guiomar R, Costa I, Haveri A, Holzer B, Korukluoğlu G, Nguyen T, Pakarna G, Pancer K, Trilar KP, Protic J, Stojanović M, De Santis R, Lista F, Vremera T, Leustean M, Pistol A, Zelena H, Reusken C, Broberg EK. Comparative study between virus neutralisation testing and other serological methods detecting anti-SARS-CoV-2 antibodies in Europe, 2021. J Virol Methods. 2023 Dec;322:114825. doi: 10.1016/j.jviromet.2023.114825. Epub 2023 Sep 29. PMID: 37778539; PMCID: PMC10682845.
- Corona A, Madia VN, De Santis R, Manelfi C, Emmolo R, Ialongo D, Patacchini E, Messore A, Amatore D, Faggioni G, Artico M, Iaconis D, Talarico C, Di Santo R, Lista F, Costi R, Tramontano E. Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication. Antiviral Res. 2023 Sep;217:105697. doi: 10.1016/j.antiviral.2023.105697. Epub 2023 Aug 9. PMID: 37562607.
- Manzi S, Nelli L, Fortuna C, Severini F, Toma L, Di Luca M, Michelutti A, Bertola M, Gradoni F, Toniolo F, Sgubin S, Lista F, Pazienza M, Montarsi F, Pombi M. A modified BG-Sentinel trap equipped with FTA card as a novel tool for mosquito-borne disease surveillance: a field test for flavivirus detection. Sci Rep. 2023 Aug 8;13(1):12840. doi: 10.1038/s41598-023-39857-1. PMID: 37553350; PMCID: PMC10409816.
- Manna A, De Forni D, Bartocci M, Pasculli N, Poddesu B, Lista F, De Santis R, Amatore D, Grilli G, Molinari F, Sangiovanni Vincentelli A, Lori F. SARS-CoV-2 Inactivation in Aerosol by Means of Radiated Microwaves. Viruses. 2023 Jun 27;15(7):1443. doi: 10.3390/v15071443. PMID: 37515131; PMCID: PMC10386662.
- Lista F, Peragallo MS, Biselli R, De Santis R, Mariotti S, Nisini R, D'Amelio R. Have Diagnostics, Therapies, and Vaccines Made the Difference in the Pandemic Evolution of COVID-19 in Comparison with "Spanish Flu"? Pathogens. 2023 Jun 23;12(7):868. doi: 10.3390/pathogens12070868. PMID: 37513715; PMCID: PMC10384375.
- Faggioni G, De Santis R, Moramarco F, Di Donato M, De Domenico A, Molinari F, Petralito G, Fortuna C, Venturi G, Rezza G, Lista F. Pan-yellow fever virus detection and lineage assignment by real-time RT-PCR and amplicon sequencing. J Virol Methods. 2023 Jun;316:114717. doi: 10.1016/j.jviromet.2023.114717. Epub 2023 Mar 25. PMID: 36972832.
- De Santis R, Faggioni G, Amoroso A, Ciammaruconi A, Pomponi A, Stella Lia M, Amatore D, Molinari F, Petralito G, Stefanelli P, Rezza G, Lista F. Durability of neutralizing antibodies against yellow fever virus after vaccination in healthy adults. Vaccine. 2023 Apr 24;41(17):2761-2763. doi: 10.1016/j.vaccine.2023.03.022. Epub 2023 Mar 24. PMID: 36967285.
- Lo Presti A, Carannante A, Fazio C, Neri A, Vacca P, Ambrosio L, Lista F, Fillo S, Stefanelli P. FHbp variants among meningococci of serogroup B in Italy: Evolution and selective pressure, 2014-2017. PLoS One. 2023 Feb 16;18(2):e0277976. doi: 10.1371/journal.pone.0277976. PMID: 36795654; PMCID: PMC9934395.
- Carannante A, Vacca P, Fontana S, Dal Conte I, Ghisetti V, Cusini M, Prignano G, Vocale C, Barbui AM, Stroppiana E, Busetti M, Mencacci A, Rotondi M, De Francesco MA, Bonanno CL, Innocenti P, Latino MA, Riccobono E, Poletti F, Casonato IC, Soldato G, Ambrosio L, Boros S, Ciammaruconi A, Lista F, Stefanelli P. Seven Years of Culture Collection of Neisseria gonorrhoeae: Antimicrobial Resistance and Molecular Epidemiology. Microb Drug Resist. 2023 Mar;29(3):85-95. doi: 10.1089/mdr.2021.0483. Epub 2023 Feb 8. PMID: 36757312; PMCID: PMC10024589.
- Fraternale A, De Angelis M, De Santis R, Amatore D, Masini S, Monittola F, Menotta M, Biancucci F, Bartoccini F, Retini M, Fiori V, Fioravanti R, Magurano F, Chiarantini L, Lista F, Piersanti G, Palamara AT, Nencioni L, Magnani M, Crinelli R. Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production. FASEB J. 2023 Feb;37(2):e22741. doi: 10.1096/fj.202201157RR. Erratum in: FASEB J. 2023 Apr;37(4):e22850. doi: 10.1096/fsb2.22850. PMID: 36583713; PMCID: PMC9880737.
2022
- Negro S, Lauria F, Stazi M, Tebaldi T, D'Este G, Pirazzini M, Megighian A, Lessi F, Mazzanti CM, Sales G, Romualdi C, Fillo S, Lista F, Sleigh JN, Tosolini AP, Schiavo G, Viero G, Rigoni M. Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor. Acta Neuropathol Commun. 2022 Dec 25;10(1):189. doi: 10.1186/s40478-022-01495-5. PMID: 36567321; PMCID: PMC9791753.
- Stefanelli P, Trentini F, Petrone D, Mammone A, Ambrosio L, Manica M, Guzzetta G, d'Andrea V, Marziano V, Zardini A, Molina Grane' C, Ajelli M, Di Martino A, Riccardo F, Bella A, Sane Schepisi M, Maraglino F, Poletti P, Palamara AT, Brusaferro S, Rezza G, Pezzotti P, Merler S; Genomic SARS–CoV–2 National Surveillance Working Group; Italian Integrated Surveillance of COVID–19 Study Group; Italian Integrated Surveillance of COVID-19 Study Group; Genomic SARS-CoV-2 National Surveillance Working Group. Tracking the progressive spread of the SARS-CoV-2 Omicron variant in Italy, December 2021 to January 2022. Euro Surveill. 2022 Nov;27(45):2200125. doi: 10.2807/1560-7917.ES.2022.27.45.2200125. PMID: 36367013; PMCID: PMC9650705.
- Biselli R, Nisini R, Lista F, Autore A, Lastilla M, De Lorenzo G, Peragallo MS, Stroffolini T, D'Amelio R. A Historical Review of Military Medical Strategies for Fighting Infectious Diseases: From Battlefields to Global Health. Biomedicines. 2022 Aug 22;10(8):2050. doi: 10.3390/biomedicines10082050. PMID: 36009598; PMCID: PMC9405556.
- Antonelli G, Focosi D, Turriziani O, Tuccori M, Brandi R, Fillo S, Ajassa C, Lista F, Mastroianni CM. Virological and clinical rebounds of COVID-19 soon after nirmatrelvir/ritonavir discontinuation. Clin Microbiol Infect. 2022 Dec;28(12):1657-1658. doi: 10.1016/j.cmi.2022.06.029. Epub 2022 Jul 2. Erratum in: Clin Microbiol Infect. 2024 Mar;30(3):408. doi: 10.1016/j.cmi.2023.12.014. PMID: 35792281; PMCID: PMC9250152. Antonelli G, Focosi D, Turriziani O, Tuccori M, Brandi R, Fillo S, Ajassa C, Lista F, Mastroianni CM. Virological and clinical rebounds of COVID-19 soon after nirmatrelvir/ritonavir discontinuation. Clin Microbiol Infect. 2022 Dec;28(12):1657-1658. doi: 10.1016/j.cmi.2022.06.029. Epub 2022 Jul 2. Erratum in: Clin Microbiol Infect. 2024 Mar;30(3):408. doi: 10.1016/j.cmi.2023.12.014. PMID: 35792281; PMCID: PMC9250152.
- Fazio C, Daprai L, Neri A, Tirani M, Vacca P, Arghittu M, Ambrosio L, Cereda D, Gramegna M, Palmieri A, Carannante A, Bertoli MR, Crottogini L, Gennati G, Quinz E, Trezzi L, Ciammaruconi A, Fillo S, Fortunato A, Rezza G, Lista F, Stefanelli P. Reactive vaccination as control strategy for an outbreak of invasive meningococcal disease caused by Neisseria meningitidis C:P1.5-1,10-8:F3-6:ST-11(cc11), Bergamo province, Italy, December 2019 to January 2020. Euro Surveill. 2022 Jun;27(24):2100919. doi: 10.2807/1560-7917.ES.2022.27.24.2100919. PMID: 35713021; PMCID: PMC9205164.
- Gattuso A, Cella E, Fillo S, Ortoffi MF, Angeletti S, Ciccozzi M, De Medici D, Lista F, Fiore A. Phylogenetic and Evolutionary Genomic Analysis of Listeria monocytogenes Clinical Strains in the Framework of Foodborne Listeriosis Risk Assessment. Front Microbiol. 2022 Apr 1;13:816880. doi: 10.3389/fmicb.2022.816880. PMID: 35432277; PMCID: PMC9010861.
- Lo Presti A, Di Martino A, Faggioni G, Giordani F, Fillo S, Anselmo A, Fain VV, Fortunato A, Petralito G, Molinari F, Palomba S, De Santis R, Fiore S, Fabiani C, Di Mario G, Facchini M, Calzoletti L, Lista F, Rezza G, Stefanelli P. Analysis of Genomic Characteristics of SARS-CoV-2 in Italy, 29 January to 27 March 2020. Viruses. 2022 Feb 25;14(3):472. doi: 10.3390/v14030472. PMID: 35336879; PMCID: PMC8951147.
- Marazzato M, Scribano D, Sarshar M, Brunetti F, Fillo S, Fortunato A, Lista F, Palamara AT, Zagaglia C, Ambrosi C. Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-Resistant Acinetobacter baumannii Isolates. Int J Environ Res Public Health. 2022 Mar 1;19(5):2870. doi: 10.3390/ijerph19052870. PMID: 35270562; PMCID: PMC8910769.
- Ricci ML, Fillo S, Ciammaruconi A, Lista F, Ginevra C, Jarraud S, Girolamo A, Barbanti F, Rota MC, Lindsay D, Gorzynski J, Uldum SA, Baig S, Foti M, Petralito G, Torri S, Faccini M, Bonini M, Gentili G, Senatore S, Lamberti A, Carrico JA, Scaturro M. Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains. Life Sci Alliance. 2022 Mar 2;5(6):e202101117. doi: 10.26508/lsa.202101117. PMID: 35236759; PMCID: PMC8899845.
- Stazi M, Fabris F, Tan KY, Megighian A, Rubini A, Mattarei A, Negro S, D'Este G, Lista F, Rossetto O, Tan CH, Montecucco C. An agonist of the CXCR4 receptor is therapeutic for the neuroparalysis induced by Bungarus snakes envenoming. Clin Transl Med. 2022 Jan;12(1):e651. doi: 10.1002/ctm2.651. PMID: 35075797; PMCID: PMC8787102.
- Furlani F, Rossi A, Grimaudo MA, Bassi G, Giusto E, Molinari F, Lista F, Montesi M, Panseri S. Controlled Liposome Delivery from Chitosan-Based Thermosensitive Hydrogel for Regenerative Medicine. Int J Mol Sci. 2022 Jan 14;23(2):894. doi: 10.3390/ijms23020894. PMID: 35055097; PMCID: PMC8776110.
- Fabiani L, Mazzaracchio V, Moscone D, Fillo S, De Santis R, Monte A, Amatore D, Lista F, Arduini F. Paper-based immunoassay based on 96-well wax-printed paper plate combined with magnetic beads and colorimetric smartphone-assisted measure for reliable detection of SARS-CoV-2 in saliva. Biosens Bioelectron. 2022 Mar 15;200:113909. doi: 10.1016/j.bios.2021.113909. Epub 2021 Dec 23. PMID: 34995838; PMCID: PMC8697482.
